Erythropoietin
Site of synthesis
Kidneys
Function:
1. Increases proliferation of BFU-E cells
2. Speeds up maturation of all erythroid precursors
3. Shortens the time retics spend in the bone marrow
Normal time is
3 days in bm and 1 day in pb
Elevated
levels seen in:
Renal tumors
Leads to secondary
polycythemia