Intravascular
Features
1. Accounts
for 10% of aged cell destruction
2. Decreased
levels of haptoglobin seen in plasma
3. Decreased
levels of hemopexin seen in plasma
4. Methemoglobinemia
5. Methemoglobinuria
6. Colors
associated with various hemoglobins:
Pink =
Free hemoglobin
Red =
Oxyhemoglobin
Brown =
Methemoglobin
7. Excess
iron:
Stored as hemosiderin and ferritin
Excess iron filtered by renal
glomerulus and absorbed by renal tubular cells
Hemosiderinuria results