Intravascular Hemolysis
Old or damaged RBC’s hemolyzed as
they circulate
Free hgb
ab
dimers of Hgb
haptoglobin
Haptoglobin+ Hgb complex or hemopexin+
Methgb enter liver and same process as
extravascular hemolysis occurs
Methemoglobin
(Fe
+++
)
hemopexin
Methemoglobin (Fe
+++
)
albumin
Methemalbumin
hemopexin