CLSC412 HEMOSTASIS

Intravascular - Anemias

1. Complement activated:

2. Physical or mechanical trauma:

3. Toxic microenvironment:

h Paroxysmal Nocturnal Hemoglobinemia

h Paroxysmal Cold Hemoglobinemia

h Autoimmune hemolytic anemias

h Alloimmune hemolytic anemias - IgM

h Microangiopathic hemolytic anemias (MAHA)

h Osmotic trauma

h Heart & vessel abnormalities

h Prosthetic heart valves

h D.I.C.

h Bacterial & Parasitic infections

h Venoms & Drugs