Killing
Process
Granular
contents released into phagosome: (non-oxygen
dependent killing:
Bactericidal
activity of lytic enzymes cleaves segments of the antigen and
changes pH
Oxygen-dependent
killing:
Release
of nictinomide adenine dinucleotide phosphate (NADPH) oxidase which
in turn causes superoxides and hydrogen peroxide to be
formed
Called
the “respiratory burst”
Superoxides
join with myeloperoxidase to form hydrochlorous acid (bleach)