Cytochemical Classification-3
Periodic Acid-Schiff test:
Oxidizes complex CHO’s to aldehydes that react with reagent to form red precipitate. Positive in all cells
Differentiation is based on pattern of reactivity:
Granulocytes:
Strongly positive
Megakaryocytes:
Platelets:
ALL:
Diffusely positive
Intense red-pink positive
Course block pattern positive
Fine diffuse pattern positive
Combination of both or negative