Zinc Protophorphyrin
Heme synthesis:
Review heme synthesis from unit 5
Structure into which iron is inserted:
Protoporhyrin IX
Fe
++
State iron is in when forming heme structure
Iron deficiency anemia
Diseases in which zinc replaces iron in heme structure:
Because iron is unavailable zinc is
inserted into protoporphyrin IX structure
Lead poisoning
Because iron is inhibited from insertion,
zinc is inserted into protoporphyrin IX
structure