Thrombin
Time - 2
Normal range:
10 – 14 seconds
Clinical application:
Used to measure functional factor I
levels
Will be prolonged in:
hypofibrinogenemia
dysfibrinogenemia
afibrinogenemia
Will also be prolonged if fibrin
split products (FSP) are present, patient on streptokinase therapy, during pregnancy, in newborns, or patients
with multiple myeloma
Heparin therapy