Platelet
Aggregation Studies - 1
Function:
Measures primary hemostasis,
specifically platelet function
Specimen requirements:
Platelet Rich Plasma (PRP) made by
cetrifuging anticoagulated
blood with reduced force so platelets stay in plasma section.
Principle of test:
PRP is placed in tube and tube
placed into aggregometer. An aggregating agent is added the change in optical density is
plotted. As the platelets aggregate the solution becomes less turbid.
In vitro aggregating agents:
ADP, epinephrine, collagen,
ristocetin