Waldenstrom=s - 3
•Mechanism of Disease:
•ecause unknown
•egenetic predisposition may play a role
•emainly seen in older individuals
•epresents with the following features:
•Žmalignant proliferation of B cell line
•Žincreased plasma cell population
•Žhigh levels of IgM produced
•Žweakness, fatigue, nose & gum bleeds, and GI bleeds leads to anemia
•Žincreased infections
•Žweight loss
•Žincreased blood viscosity
•Žmay develop neurological and cardiac problems