Inflammation - 7
•Types of inflammatory reactions: - continued
•eImmune-complex-Mediated Inflammation - type III hypersensitivity
•ŽMechanisms of response:
•IgG capable of activating complement or IgM that does activate complement, are formed and react with the inducing antigen to form ag-ab complexes within the circulatory system.
•These immune-complexes are then deposited on or in various tissues such as:
•]glomerular basement membrane (Goodpasture's syndrome)
•]endothelial cells of blood vessels