Markers & Receptors - 2
•Definition:
•Cell markers are molecules expressed on the surface of normal cells that may act as receptors (attachment sites) for other molecules or be unique markers that help identify a lineage of cells
•Receptors for antigens:
•eAll immune cells except natural killer cells (NK) have molecular receptors for the recognition of specific antigens
•eExamples of these molecular receptors include:
•ŽT-cell receptors (TCR=s)
•ŽB-cell receptors (BCR=s)
•all are surface immunoglobulins (sIgs)
•ŽCD3 proteins
•work in conjunction with TCR=s
•ŽMajor Histocompatibility Complex molecules