Immunoglobulin Diversity - 2
Immunoglobulin
genes:
eChromosomes do not contain genes for immunoglobulin
synthesis
eChromosomes contain multiple coding segments (building
blocks) from which developing B lymphocytes assemble the
immunoglobulin genes
eThese multiple coding segments are called exons
when incoporated into the B lymphocyte=s DNA molecule
eThese exons are seperated by non-coding DNA
segments called introns
eThe recombination of immunoglobulin exons to form functional
genes takes place whenever the B lymphocyte (plasma cell)
needs to produce more immunoglobulins.
