Immunoglobulin Fragmentation - 2
History:
e1962 - Rodney Porter proposed the basic structure
of the immunoglobulin molecule
eUsed proteolytic enzymes to cleave rabitt IgG
eThese proteolytic enzymes were:
Žpapain
Žpepsin
eThe results of treatment with these enzymes was the
production of different fragments of the IgG molecule
