Graft-vs-Host Reaction - 2
•Initiation of Host-vs-Graft Reactions:
•Initiation of Graft-vs-Host Reactions:
•ein allografts (grafts between same species) that differ from a recipient at the class I and class II MHC loci (resulting in dissimilar antigenic molecules), both the CD8+ and CD4+ cells of the host become activated and the resulting immune response is against the grafted tissue of donor
•ein allografts (grafts between same species) that differ from a recipient at the class I and class II MHC loci (resulting in dissimilar antigenic molecules), both the CD8+ and CD4+ donor cells become activated and the resulting immune response is against the tissues of the host (recipient)