

Graft-vs-Host Reaction - 3
•Conditions
that may cause a Graft-vs-Host Reaction:
•ethere are
differences in tissue histocomaptibility between donor and host
•ethe host is
immunocompromised
•ethe graft
cells are immunocompetent and are able to trigger an
immune reaction against host tissue
•eprocedures or
products that may cause GVD when immunocompetent lymphocytes are
present include:
•Žintrauterine
transfusions
•Žblood
transfusions - whole, packed, or frozen
•Žplasma
transfusions - fresh or frozen
•Žtransplantation
of fetal thymus
•Žtransplantation
of fetal liver
•Žtransplantation
of bone marrow