Graft-vs-Host Reaction - 3
•Conditions that may cause a Graft-vs-Host Reaction:
•ethere are differences in tissue histocomaptibility between donor and host
•ethe host is immunocompromised
•ethe graft cells are immunocompetent and are able to trigger an immune reaction against host tissue
•eprocedures or products that may cause GVD when immunocompetent lymphocytes are present include:
•Žintrauterine transfusions
•Žblood transfusions - whole, packed, or frozen
•Žplatelet transfusions
•Žplasma transfusions - fresh or frozen
•Žtransplantation of fetal thymus
•Žtransplantation of fetal liver
•Žtransplantation of bone marrow