

Graft-vs-Host Reaction - 4
•Graft-vs-Host
Reaction (GVD) and Graft-vs-Host Disease (GVHD):
•ewhen the
Graft-vs-Host reaction injures the host tissues such that loss
of function occurs in the affected area, it is then called
Graft-vs-Host Disease (GVHD).
•Classification
of Graft-vs-Host Disease (GVHD):
•ebased on the
histiologic pattern observed at site of tissue injury
•wepithelial
cells necrosis in:
•-skin, liver,
and GI tract
•wrash,
jaundice, diarrhea, and pulmonary infiltrates
•wdeath may
result from increased susceptibility to infections