Graft-vs-Host Reaction - 4
•Graft-vs-Host Reaction (GVD) and Graft-vs-Host Disease (GVHD):
•ewhen the Graft-vs-Host reaction injures the host tissues such that loss of function occurs in the affected area, it is then called Graft-vs-Host Disease (GVHD).
•Classification of Graft-vs-Host Disease (GVHD):
•ebased on the histiologic pattern observed at site of tissue injury
•Žacute GVHD:
•wepithelial cells necrosis in:
•-skin, liver, and GI tract
•wrash, jaundice, diarrhea, and pulmonary infiltrates
•wdeath may result from increased susceptibility to infections