Graft-vs-Host Reaction - 5
Classification
of Graft-vs-Host Disease (GVHD): continued
Žchronic GVHD:
wpresence of
fibrosis and atrophy of one of the target sites:
-skin, liver,
and GI tract
wdysfunction of
target site may lead to death
woccurs in
patients that have severe immunodeficiency
woccurs in
immunodeficient patients that have received transfusions containing immunocompetent
lymphocytes within 5 - 30 days
wsecondary
infections are frequently seen in patients with GVHD
