Graft-vs-Host Reaction - 6
•Mechanism:
•enot well understood
•eNatural killer cells (NK) act as effector cells
•ebelief is that IL-2 activates NK cells to become lymphokine-activated killer cells (LAK)
•eNK cells are seen attached to dying epithelial cells
•eLAK cells are not MHC-restricted and are able to lyse host cells