Responses
to Foreign Material
Three responses to foreign material
(antigen) - see table 1-1 on page 7
1.Natural
(nonspecific or innate) immune response
2.Specific
(acquired) immune response
3.Tolerance
˜the body=s first defense mechanisms
˜those defense
mechanisms one is born with:
&anatomic
barriers (skin, mucous membranes)
&physiological
barriers (temp, pH, mediators)
&phagocytic
barriers (neutrophils, macrophages)
&inflammatory
barriers (serum proteins)
˜the immune
systems response to contact with antigen
˜Humoral
immunity (B-cells = immunoglobulins)
˜Cell-mediated
immunity (T-cells)
immunity
