Specific
(Acquired) Immunity - 3
1.Mechanism: - see figure 1-7 on page 16
Humoral Immune Response
Extracellular
antigens (mainly bacteria) and certain intracellular antigens (those that migrate
between cells i.e. malaria)
are detected by the immune system and antigen presenting cells (APC=s) phagocytize them.
The processed
antigen is then expressed on the APC=s
surface bound to
class II MHC (Major Histocompatibility Complex) molecules.
The class II
MHC (Major Histocompatibility Complex) bound antigen is then detected by THelper lymphocytes (CD4+) by the T cell receptor (TCR) which is also
associated with the CD3
receptor. - see figure 1-9 on page 18
