Specific
(Acquired) Immunity - 7
3.Major immunologic events during specific
immune responses
Cell-Mediated Immune Response
Cognitive phase
(recognition phase in humoral)
LCD4+ binds
with MHC II bound antigen
LCD8+ binds
with MHC I bound antigen
Activation
phase (proliferation & differentiation in humoral)
LCD4+ produces
cytokines that:
Nstimulates
macrophage phagocytosis
Nstimulates B
cells to differentiate into plasma cells & memory cells
Nstimulates
CD8+ to form cytotoxic function
LCD8+ produces
cytokines that:
Nstimulates
CD8+ to form cytotoxic function
