Inflammation
- 5
Types of inflammatory reactions: -
continued
eAntibody-Mediated
Inflammation - type I hypersensitivity
ŽMechanisms
of response:
IgE produced
in response to initial stimulation of immune system
IgE binds to
IgE (Fc) receptors on mast cells/basophils (@sensitization@)
when
allergen (antigen) binds with more than two IgE molecules on mast cell/basophil it causes cell to release granular contents (@degranulation@)
granular
mediators released
ŽMediator
induced changes that take place:
infiltration
by cells
erythema,
heat, & itching
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