Inflammation
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•Types of inflammatory reactions: -
continued
•eImmune-complex-Mediated Inflammation - type
III hypersensitivity
•ŽMechanisms of response:
•IgG capable
of activating complement or IgM that does activate complement, are formed and react with the inducing antigen to form ag-ab complexes within the circulatory system.
•These
immune-complexes are then deposited on or in various tissues such as:
•]glomerular
basement membrane (Goodpasture=s syndrome)
•]endothelial
cells of blood vessels