Vaccine Design - 2
•
Types of vaccine formulations (designs):
•
e
attenuated
•
e
synthetic antigen
•
e
live viral vector
•
e
Subunits
•
e
Naked DNA
•
Attenuated vaccines:
•
e
First type of vaccines used
•
e
Still used for the following:
•
Ž
Mycobacterium tuberculosis
•
Ž
Salmonella typhii
•
Ž
Bordetella pertussis
•
e
short-lived and limited protection
•
e
Live attenuated viral vaccines are more effective than are
killed ones:
•
Ž
Polio vaccines
•
Ž
Measles vaccines
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