Proteins
as Antigens
Types of antigens: - continued
1.Proteins
˜induces
strong humoral and cell-mediated responses
˜produces
long-lasting immunologic memory
˜recognition
by T lymphocytes is MHC restricted
&peptides
bound to class I MHC
Umainly from
intracellular organisms
Urecognized by
TCR=s of CD8+ cells
&peptides
bound to class II MHC
Umainly from
extracellular organisms
Uprocessed by
antigen-presenting cells
UMHC II bound
peptides are recognized by TCR=s
of CD4+ cells
