Macromolecules & Synthetic Antigens
•Types of antigens: - continued
•3.Macromolecules
•˜induce a humoral immune response
•˜larger than the antigen-binding portion of antibody
•˜contains multiple epitopes that will bind with idiotope
•4.Synthetic
•˜chemically synthesized short peptides
•˜sequence of amino acids from known infectious agents
•˜act as haptens
•˜used as vaccines but limited use due to:
•Udoes not induce immunologic memory against hapten but rather against carrier molecule