MHC
Antigens
Types of antigens: - continued
5.Major
Histocompatibility Complex (MHC)
˜tissue
antigens are found on surface of cells:
UHLA-A, HLA-B,
HLA-C
Ualso called
alloantigens or class I MHC antigens
˜class II MHC
antigens are:
UHLA-DR,
HLA-DP, and HLA-DQ
˜most
polymorphic genes of human genome
˜participate
in recognition of self and foreign antigens
˜triggers
rejection of incompatible tissue grafts
˜serves as
specific tissue markers that reflects genetic makeup of individual
