Antigen Classification - 2
•Definition:
•antigens can be classified according to site of infectivity as:
•˜Intracellular (Endogenous) antigen
•ˆinside the cell
•ˆnot directly accessible to immune system
•ˆactivates cell-mediated immune system
•ˆeffector cells are Tcytotoxic and destroy both the infected cell and the antigen
•ˆexamples of organisms are:
•Nviruses
•HIV, Hepatitis
•Nintracellular organisms like:
•%bacteria
•M. tuberculosis
•%rickettsia
•R. rickettsii