Tumor
Markers - 12
Gene/chromosome markers:
eThere are a
couple of markers that are used in diagnosis:
Žp53 gene:
mutated form
seen in:
hcolorectal
cancer
ŽPh1 chromosome
also called
the Philadelphia chromosome
mutated form
of chromosome is a translocation from chromosome 22 to chromosome 9 (t9,22)
h85% of CML
(chronic myelogenous leukemia)
patients have this chromosome
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