CD8-Lymphocytes
- 1
Specific Cell Characteristics: cont=d
1.Lymphocytes - continued
˜Tcytotoxic - lymphocyte functions:
eonly
recognize antigen that is:
Ubound to MHC
class I molecules on surface
of infected (target) cells
Uin
association with TCR/CD3 and CD8 receptors on Tcytotoxic -
lymphocyte
e lysis of
target cell (infected cell) is done by:
Usecretion of
toxins from granules that block ions and H2O
from leaving cell resulting in swelling
Uactivation of
target cell intracellular enzymes resulting in degradation of DNA and cell lysis
eTcytotoxic cells are not destroyed in process of lysing target cells
