B-Lymphocytes - 1
•Specific Cell Characteristics: cont=d
•1.Lymphocytes - continued
•˜ B - lymphocyte characteristics:
•ematuration occurs in the bone marrow
•esecrete immunoglobulins onto surface membranes
•ematuration stages:
•UPre-B lymphocyte
•-lacks ability to recognize or respond to antigen
•UImmature-B lymphocyte
•-has IgM on surface
•-lacks ability to proliferate or differentiate in response to antigen
•-stage in which self-tolerance develops