Cytokines - 2
•Three functional groups of cytokines: cont=d
•eMediators and regulators of specific immune responses.
•Cytokine
•Produced by
•Target cell
• effects            
•IL-2
•IL-4
•IL-5
•IFN-(
•T-cells
•T & NK-cells
•proliferation of antigen- specific cells & other immature cells
•T4 cells
•B-cells
•antibody switching to IgE
•T-cells
•B-cells
•growth & differentiation of eosinophils
•T8, Th1 & NK
•most cells
•B-cell activation, T-cell production of MHC-I, Th1 production of IL-2 and IL-2R
•Cytokines