Complement Nomenclature
•Nomenclature of complement system:
•eClassical pathway & MAC
•Uidentified by numbers and letters:
•mC3i, C5i, etc. designate the zymogen (inactive form)
•     __    __
•mC3a, C5b, etc. designate the protease (active form)
•mduring proteolysis to form proteases fragments are split off:
•-large fragment called Aa@ (i.e. C3a)
•-small fragment called Ab@ (i.e. C3b)
•eAlternative pathway & MAC
•Uidentified by letters preceded by factor:
•mfactor B, factor H, etc.
•Cytokines