Role of Lymphocytes - 4
•T-cell Dependent Antigen:
•eB cell acts as antigen-presenting cell
•eantigen recognition is MHC restricted
•erequires interaction of T-cells with B-cells
•T-cell Independent Antigen
•edoes not requires T cells interaction
•eB-cells are activated when antigen comes in contact
•eAntigens that may act in this way include:
•Ulipopolysaccharides
•Uproducts of bacteria
•eMacrophages are stimulated to secrete cytokines
•UIl-1
•UIL-6
•UTNF"
•eresponse is not long lasting
•eno IgG produced
•eonly IgM produced