Production of Immunoglobulins - 1
•Initiation of humoral immune response:
•eantigen recognition by CD4+ t-cells
•eactivation of:
•Umature B-cells
•Umemory B-cells
•eculminates in production of plasma cells
•esynthesis and secretion of antigen-specific antibodies such as:
•UB-cell receptors
•-also known as surface immunoglobulins (sIg)
•-secreted by B-cells and are bound to their surface
•-bind antigen at the variable region of sIg.