B-Lymph Development - 1
•Characteristics of Stages in B lymphocyte development:
•ePluripotential Stem Cell
•Ua cell found in bone marrow that may differentiate into any cell line (myeloid or lymphoid)
•eLymphoid Stem cell
•Ua cell found in bone marrow that may differentiate into any lymphoid cell line)
•ePre-B lymphocyte
•U1st cell of B-cell lineage to show : heavy chain
•Ufound only in bone marrow or fetal liver
•Udo not express functional IgM on surface
•Ucannot bind or respond to antigens