Immunoglobulin
Molecules - 1
eForm
Ueach B-cell
has the ability to synthesize and secrete two forms of Igs:
-cell surface
immunoglobulins (sIgs)
-secreted
immunoglobulins (antibodies)
Uboth forms
are structurally similar
Uboth forms
show the same antigenic specificity
eSurface Immunoglobulins (BCR=s or sIgs)
Uhas an
additional segment of amino acids at the carboxyl end of heavy chain (Fc portion)
which anchors it
to cell membrane
Usince they
are only found on B-cells they act as B-cell markers
Ualso serve as
antigen receptors
