Secreted
Immunoglobulin - 3
eSecreted Immunoglobulins (Abs) - continued
UHeterophil antibodies
-associated with
infectious mononucleosis caused by Epstein-Barr virus (EBV)
-may also be
present in healthy individuals at low titer
-they are
non-specific in that they are produced against one antigen but can react with other antigens from other species
-Paul-Bunnell
test and Davidsohn differential test are based on detection of heterophil abs in 80 - 90% of patients with IM due to EBV
