Immunoglobulin Chains - 2
•
U
Heavy chains - cont
=
d
•
-classes of immunoglobulins based on type
of heavy chain are:
•
L
IgG
•
L
IgM
•
L
IgA
•
L
IgD
•
L
IgE
•
-
(
(gamma) type heavy chains
•
-
:
(Mu) type heavy chains
•
-
"
(alpha) type heavy chains
•
-
2
(delta) type heavy chains
•
-
,
(epsilon) type heavy chains
•
U
Regions of immunoglobulin molecule
•
-Variable region
•
-Hypervariable region
•
-Constant region
•
-Hinge region
•
-antigen-binding sites
•
-antigen-binding sites
•
-biological activity
•
-gives molecule flexibility