Specificity
& Bonds
eAntibody specificity
the
immunoglobulin recognizes the general configuration of the particular epitope
that is complementary
to it=s binding site
(paratope)
eBond
formation:
Ubonds form
between amino acides of paratope and the molecules of epitope and may be of the
following types:
1.ionic bonds:
2.hydrogen
bonds:
3.hydrophobic
bonds:
4.van der Waals
forces:
opposite
charges attract
polar molecules
with COO- join with H+
nonpolar
molecules exclude H2O
interaction of
external electron clouds
