Immunoglobulin
Diversity - 2
Immunoglobulin genes:
eChromosomes do not contain genes for
immunoglobulin synthesis
eChromosomes contain multiple coding segments
(building blocks) from
which developing B lymphocytes assemble the immunoglobulin genes
eThese multiple coding segments are called
exons when incoporated
into the B lymphocyte=s
DNA molecule
eThese exons are seperated by non-coding DNA
segments called
introns
eThe recombination of immunoglobulin exons to
form functional
genes takes place whenever the B lymphocyte (plasma cell) needs to produce more
immunoglobulins.
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