Immunoglobulin
Fragmentation - 2
History:
e1962 - Rodney Porter proposed the basic
structure of the immunoglobulin
molecule
eUsed proteolytic enzymes to cleave rabitt
IgG
eThese proteolytic enzymes were:
Žpapain
Žpepsin
eThe results of treatment with these enzymes
was the production
of different fragments of the IgG molecule
