Function
of MHC - I
USpecific Tissue Markers:
URecognition of Foreign Antigen:
UGraft Rejection:
-reflects the unique genetic makeup of
individual
-able to bind endogenous proteins on virally
altered cells
-serve as antigen-presenting cells
-serve as target cells (due to virus inside)
-CD8+ cells recognize antigen bound to MHC I
-the principle antigen recognized by
recipient=s immune system after tissue transplantation
