Acute Graft Rejection - 1
•
-Characteristics:
•
]
two types of acute graft rejection:
•
v
vascular type
•
v
cellular type
•
]
occurs within days or weeks of graft
•
-Mechanism:
•
]
vascular type:
•
v
IgG + C
=
against endothelial cells
•
v
CD8 cells respond to Ab
=
s and :
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-lyse cells
•
-cytokines induce inflammation