Graft-vs-Host
Reaction - 3
•Conditions that may cause a Graft-vs-Host
Reaction:
•ethere are differences in tissue
histocomaptibility between donor and host
•ethe host is immunocompromised
•ethe graft cells are immunocompetent and are
able to trigger an
immune reaction against host tissue
•eprocedures or products that may cause GVD
when immunocompetent
lymphocytes are present include:
•Žintrauterine transfusions
•Žblood transfusions - whole, packed, or
frozen
•Žplasma transfusions - fresh or frozen
•Žtransplantation of fetal thymus
•Žtransplantation of fetal liver
•Žtransplantation of bone marrow