Graft-vs-Host
Reaction - 4
Graft-vs-Host Reaction (GVD) and Graft-vs-Host Disease (GVHD):
ewhen the Graft-vs-Host reaction injures the
host tissues such
that loss of function occurs in the affected area, it is then called Graft-vs-Host Disease (GVHD).
Classification of Graft-vs-Host Disease (GVHD):
ebased on the histiologic pattern observed at
site of tissue injury
Žacute GVHD:
wepithelial cells necrosis in:
-skin, liver, and GI tract
wrash, jaundice, diarrhea, and pulmonary infiltrates
wdeath may result from increased
susceptibility to
infections
