Type
I - Immediate or Allergic - 1
Description:
an immune
response (called an allergic
reaction or allergy) that is mediated by
IgE and occurs immediately after subsequent contact with same antigen (called allergen).
Mechanism of tissue damage:
Uduring 1st
contact with allergen IgE production is initiated by TH2 response to allergen.
UIgE produced
bind to mast cells via Fc receptors and mast cells are said to be sensitized.
mast cell
Fc receptors
IgE
Sensitized mast
cell
