Type
I – Immediate or Allergic - 2
Mechanism of tissue damage: - cont=d
Uin subsequent
allergen exposure the allergen binds with IgE on sensitized mast cells
allergen must
bind to 2 or more IgE
molecules before mast cell
will secrete mediators:
eosinophil
chemotactic factor
histamine
prostaglandins
Sensitized mast
cell