Type
II – Goodpasture’s Syndrome
Uthe reaction occurs when:
]antigen/antibody
complexes form along basement membranes of glomeruli and alveoli
]complement
is activated via classical pathway by complexes and MAC is responsible for tissue
damage
]neutrophils
accumulate at site of injury and release enzymes adding to injury
Uthe reaction=s features :
]autoantibodies
formed against collagen of basement membranes
]lesions
form in both lungs and kidneys
